Pseudallescheria boydii cranial osteomyelitis and subdural empyema successfully treated with voriconazole: a case report and literature review

Z A Kanafani; Y Comair; S S Kanj

doi:10.1007/s10096-004-1233-2

Pseudallescheria boydii cranial osteomyelitis and subdural empyema successfully treated with voriconazole: a case report and literature review

Eur J Clin Microbiol Infect Dis. 2004 Nov;23(11):836-40. doi: 10.1007/s10096-004-1233-2. Epub 2004 Oct 19.

Authors

Z A Kanafani¹, Y Comair, S S Kanj

Affiliation

¹ Division of Infectious Diseases, American University of Beirut Medical Center, Hamra, P.O. Box 113-6044, 110 32090 Beirut, Lebanon.

PMID: 15558341
DOI: 10.1007/s10096-004-1233-2

Abstract

Described here is a case of Pseudallescheria boydii cranial osteomyelitis and subdural empyema following craniotomy, which was successfully treated with surgical debridement and voriconazole. Other reported cases of Pseudallescheria boydii osteomyelitis are reviewed. The reported case suggests that voriconazole may represent a new therapeutic option for this infection.

Publication types

Case Reports
Review

MeSH terms

Adult
Antifungal Agents / therapeutic use*
Empyema, Subdural / drug therapy*
Empyema, Subdural / microbiology
Female
Humans
Mycoses / drug therapy*
Mycoses / microbiology
Osteomyelitis / drug therapy*
Osteomyelitis / microbiology
Pseudallescheria / drug effects
Pseudallescheria / isolation & purification*
Pyrimidines / therapeutic use*
Triazoles / therapeutic use*
Voriconazole

Substances

Antifungal Agents
Pyrimidines
Triazoles
Voriconazole