Asmarines I, J, and K and nosyberkol: four new compounds from the marine sponge Raspailia sp

J Nat Prod. 2004 Nov;67(11):1932-5. doi: 10.1021/np049834b.

Abstract

Five asmarines, the known A and F and three new ones, I, J, and K, and four diterpenes, the known chelodane, barekoxide, and zaatirin and a new one, nosyberkol, were isolated from the Nosy Be Islands (Madagascar) sponge Raspailia sp. The structures of all these compounds were established on the basis of MS and NMR data. A biogenesis for the various Raspailia sp. diterpenes is suggested.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Diterpenes / chemistry
  • Diterpenes / isolation & purification*
  • Diterpenes / pharmacology
  • Drug Screening Assays, Antitumor
  • Madagascar
  • Mass Spectrometry
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Porifera
  • Tumor Cells, Cultured

Substances

  • Diterpenes
  • asmarine I
  • asmarine J
  • asmarine K