[VGKC antibodies associated with limbic encephalitis]

Nervenarzt. 2005 Jun;76(6):760-2. doi: 10.1007/s00115-004-1844-y.
[Article in German]

Abstract

Since the initial description of limbic encephalitis (LE) in 1960/1968, several subforms of this clinico-neuropathological syndrome have been identified. The best known is paraneoplastic LE. However, non-paraneoplastic forms have been reported, too. Very recently, autoantibodies against voltage-gated potassium channels have been described in association with LE. The diagnostic workup of such a case and the apparently typical good response to long-term immunotherapy of this LE subform are described.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antibodies / blood*
  • Antibodies / immunology*
  • Humans
  • Immunotherapy / methods*
  • Limbic Encephalitis / diagnosis*
  • Limbic Encephalitis / immunology*
  • Limbic Encephalitis / therapy
  • Male
  • Middle Aged
  • Potassium Channels, Voltage-Gated / immunology*

Substances

  • Antibodies
  • Potassium Channels, Voltage-Gated