Research in education assumes that every intuition regarding the improvement in the educational process is followed by justification and foundation. Creativeness and rigor with the relative implications in the context of both research and justification are the two main elements. Knowledge characteristic of the transition from a PHOG approach, that is, based on prejudice, hunches, opinions, guess, to evidence-based education is not easy to collect, document, and generalize. This approach is of even more difficult application in a highly complex context, hard to know, control and improve. To achieve high quality education, research is required for the extremely high cost of non-quality and its strong impact on medical care, social prevention and clinical research. At the university level, everyone carries out research within his/her own discipline, however all should be involved in education at large. This is particularly relevant in the medical school where education is a function of continuous improvement in health care as well as in prevention, to be implemented through health-centered educational projects.