Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation

George E Kochiadakis; Nikos E Igoumenidis; Michail E Hamilos; Panagiotis G Tzerakis; Nikos C Klapsinos; Gregory I Chlouverakis; Panos E Vardas

doi:10.1016/j.amjcard.2004.08.041

Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation

Am J Cardiol. 2004 Dec 15;94(12):1563-6. doi: 10.1016/j.amjcard.2004.08.041.

Authors

George E Kochiadakis¹, Nikos E Igoumenidis, Michail E Hamilos, Panagiotis G Tzerakis, Nikos C Klapsinos, Gregory I Chlouverakis, Panos E Vardas

Affiliation

¹ Cardiology Department, University Hospital of Heraklion, Heraklion, Crete, Greece.

PMID: 15589019
DOI: 10.1016/j.amjcard.2004.08.041

Abstract

This prospective, randomized, single-blinded, placebo-controlled study compared the efficacy and safety of sotalol and propafenone when used for long-term prevention of atrial fibrillation. For the long-term maintenance of normal sinus rhythm, propafenone seems to be more effective than sotalol.

Publication types

Clinical Trial
Comparative Study
Randomized Controlled Trial

MeSH terms

Aged
Anti-Arrhythmia Agents / therapeutic use*
Atrial Fibrillation / prevention & control*
Female
Humans
Male
Middle Aged
Propafenone / therapeutic use*
Prospective Studies
Recurrence
Safety
Sotalol / therapeutic use*

Substances

Anti-Arrhythmia Agents
Propafenone
Sotalol