Novel indirubin derivatives, promising anti-tumor agents inhibiting cyclin-dependent kinases

Int J Clin Pharmacol Ther. 2004 Nov;42(11):656-8. doi: 10.5414/cpp42656.
No abstract available

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Antineoplastic Agents / therapeutic use
  • CDC2-CDC28 Kinases / antagonists & inhibitors*
  • CDC2-CDC28 Kinases / metabolism
  • Cyclin-Dependent Kinase 2
  • Enzyme Inhibitors / pharmacology*
  • Enzyme Inhibitors / therapeutic use
  • Eye Neoplasms / drug therapy
  • Eye Neoplasms / enzymology
  • Humans
  • Indoles / pharmacology*
  • Indoles / therapeutic use
  • Phosphorylation / drug effects
  • Retinoblastoma / drug therapy
  • Retinoblastoma / enzymology
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents
  • Enzyme Inhibitors
  • Indoles
  • CDC2-CDC28 Kinases
  • CDK2 protein, human
  • Cyclin-Dependent Kinase 2
  • indirubin