Perioperative primary stroke: is aspirin cessation to blame?

Dermatol Surg. 2004 Dec;30(12 Pt 2):1526-8; discussion 1528-9. doi: 10.1111/j.1524-4725.2004.30555.x.

Abstract

Background: There are a number of reports in the literature of patients developing thrombotic events after stopping medically necessary antiplatelet and antithrombotic agents.

Objective: The objective was to determine whether discontinuation of aspirin taken for primary prophylaxis contributes to the development of thrombotic complications in patients undergoing dermatologic surgery.

Methods: A case is reported and the literature is reviewed.

Results: We present the first reported case of a postoperative thrombotic event following dermatologic surgery in a patient withholding aspirin that was taken for primary prophylaxis.

Conclusion: We believe that the available data make it difficult to implicate aspirin discontinuation in the development of each thrombotic event, given the high baseline risk of thrombotic events in the Mohs surgery patient population and the low risk of developing such events when medications are withheld perioperatively.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Aspirin / administration & dosage*
  • Carcinoma, Basal Cell / pathology
  • Carcinoma, Basal Cell / surgery
  • Diagnosis, Differential
  • Drug Administration Schedule
  • Humans
  • Male
  • Mohs Surgery / methods*
  • Nose
  • Perioperative Care*
  • Platelet Aggregation Inhibitors / administration & dosage*
  • Postoperative Complications / diagnosis
  • Skin Neoplasms / pathology
  • Skin Neoplasms / surgery
  • Stroke / diagnosis*
  • Stroke / etiology

Substances

  • Platelet Aggregation Inhibitors
  • Aspirin