The ProDom database of protein domain families: more emphasis on 3D

Catherine Bru; Emmanuel Courcelle; Sébastien Carrère; Yoann Beausse; Sandrine Dalmar; Daniel Kahn

doi:10.1093/nar/gki034

The ProDom database of protein domain families: more emphasis on 3D

Nucleic Acids Res. 2005 Jan 1;33(Database issue):D212-5. doi: 10.1093/nar/gki034.

Authors

Catherine Bru¹, Emmanuel Courcelle, Sébastien Carrère, Yoann Beausse, Sandrine Dalmar, Daniel Kahn

Affiliation

¹ Laboratoire des Interactions Plantes-Microorganismes, INRA/CNRS, BP 27, F-31326 Castanet-Tolosan Cedex, France.

Abstract

ProDom is a comprehensive database of protein domain families generated from the global comparison of all available protein sequences. Recent improvements include the use of three-dimensional (3D) information from the SCOP database; a completely redesigned web interface (http://www.toulouse.inra.fr/prodom.html); visualization of ProDom domains on 3D structures; coupling of ProDom analysis with the Geno3D homology modelling server; Bayesian inference of evolutionary scenarios for ProDom families. In addition, we have developed ProDom-SG, a ProDom-based server dedicated to the selection of candidate proteins for structural genomics.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Computer Graphics
Databases, Protein*
Genomics
Internet
Models, Molecular*
Protein Structure, Tertiary*
Proteins / chemistry
Proteins / classification
Sequence Alignment
Sequence Analysis, Protein
User-Computer Interface

Substances

Proteins