Quassinoids can induce mitochondrial membrane depolarisation and caspase 3 activation in human cells

Cell Death Differ. 2004 Dec:11 Suppl 2:S216-8. doi: 10.1038/sj.cdd.4401534.
No abstract available

Publication types

  • Letter

MeSH terms

  • Ailanthus / chemistry
  • Apoptosis / drug effects
  • Apoptosis Regulatory Proteins
  • Caspase 3
  • Caspases / drug effects*
  • Caspases / metabolism
  • Cell Line, Tumor
  • Enzyme Activation / drug effects
  • Humans
  • Jurkat Cells / drug effects*
  • Membrane Glycoproteins / pharmacology
  • Membrane Potentials / drug effects
  • Membrane Potentials / physiology
  • Mitochondria / drug effects*
  • Mitochondria / metabolism
  • Quassins / isolation & purification
  • Quassins / pharmacology*
  • Recombinant Proteins / pharmacology
  • TNF-Related Apoptosis-Inducing Ligand
  • Time Factors
  • Tumor Necrosis Factor-alpha / pharmacology

Substances

  • Apoptosis Regulatory Proteins
  • Membrane Glycoproteins
  • Quassins
  • Recombinant Proteins
  • TNF-Related Apoptosis-Inducing Ligand
  • TNFSF10 protein, human
  • Tumor Necrosis Factor-alpha
  • ailanthone
  • CASP3 protein, human
  • Caspase 3
  • Caspases