Abstract
A novel photoadduct of 4,5',8-trimethylpsoralen (TMP) and adenosine was isolated and purified by reverse-phase liquid chromatography. The structure of the photoproduct was determined by various spectral methods and found to be a TMP-adenosine 1:1 adduct resulting from the covalent bond formation between the carbon C(4) of TMP and ribose 4'-carbon of adenosine.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenosine / chemistry
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Adenosine / radiation effects*
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Molecular Structure
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Photochemistry
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Radiation-Sensitizing Agents / chemical synthesis
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Radiation-Sensitizing Agents / chemistry
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Trioxsalen / chemical synthesis
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Trioxsalen / chemistry
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Trioxsalen / radiation effects*
Substances
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Radiation-Sensitizing Agents
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Adenosine
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Trioxsalen