Abstract
The effect of prophylactic administration of ibuprofen on the cerebral circulation in preterm babies was measured with near infrared spectroscopy. No significant difference in the change in cerebral blood volume, change in cerebral blood flow, or tissue oxygenation index was found between administration of ibuprofen or placebo.
Publication types
-
Clinical Trial
-
Multicenter Study
-
Randomized Controlled Trial
MeSH terms
-
Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
-
Brain / metabolism*
-
Cerebrovascular Circulation / drug effects*
-
Double-Blind Method
-
Humans
-
Ibuprofen / pharmacology*
-
Infant, Newborn
-
Infant, Premature / physiology*
-
Oxygen / blood
-
Oxygen Consumption / drug effects*
-
Prospective Studies
-
Spectroscopy, Near-Infrared
Substances
-
Anti-Inflammatory Agents, Non-Steroidal
-
Oxygen
-
Ibuprofen