Muscle mass during childhood--relationship to skeletal development

J Musculoskelet Neuronal Interact. 2004 Mar;4(1):105-8.

Abstract

Bone densitometric data often are difficult to interpret in children and adolescents because of large inter- and intraindividual variations in bone size. Here, we propose a functional approach to bone densitometry that addresses two questions: Is bone strength normally adapted to the largest physiological loads, that is, muscle force? Is muscle force adequate for body size? To implement this approach, forearm muscle cross-sectional area (CSA) and bone mineral content (BMC) of the radial diaphysis were measured in 349 healthy subjects from 6 to 19 years of age (183 girls), using peripheral quantitative computed tomography (pQCT). This functional approach to pediatric bone densitometric data should be adaptable to a variety of densitometric techniques.

Publication types

  • Review

MeSH terms

  • Absorptiometry, Photon / methods*
  • Absorptiometry, Photon / standards
  • Adolescent
  • Adult
  • Bone Density / physiology
  • Bone Development / physiology*
  • Bone and Bones / anatomy & histology
  • Bone and Bones / diagnostic imaging
  • Bone and Bones / physiology*
  • Child
  • Female
  • Humans
  • Male
  • Muscle Contraction / drug effects
  • Muscle Contraction / physiology
  • Muscle, Skeletal / anatomy & histology
  • Muscle, Skeletal / diagnostic imaging
  • Muscle, Skeletal / physiology*
  • Skeleton*
  • Tomography, X-Ray Computed
  • Weight-Bearing / physiology