Abstract
The DNA sequence of an 8.6 kb region of the left arm of chromosome I has been determined. This region, between the LTE1 and CYS1 loci, is approximately 40 kb from the centromere. There are six potential open-reading frames (ORFs), provisionally named YAL001-006 within this fragment of chromosome I. Four of these ORFs can be aligned with previously identified FUN transcripts: FUN28 with YAL006, FUN29 with YAL004, FUN30 with YAL001 and FUN31 with YAL002. The YAL001 ORF shows significant homology to the SNF2 transcriptional regulator. A region of the DNA contains an extensive repeat of the bases C-A-T positioned in the 5' terminus of the YAL004 promoter region.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adenosine Triphosphatases
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Base Sequence
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Chromosomes, Fungal*
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Cloning, Molecular
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DNA, Fungal / genetics
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DNA-Binding Proteins / genetics*
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Deoxyribonuclease EcoRI
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Fungal Proteins / genetics*
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Genes, Fungal
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Molecular Sequence Data
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Nuclear Proteins*
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Open Reading Frames
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Saccharomyces cerevisiae / genetics*
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Saccharomyces cerevisiae Proteins*
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Sequence Homology, Nucleic Acid
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Transcription Factors / genetics*
Substances
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DNA, Fungal
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DNA-Binding Proteins
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FUN30 protein, S cerevisiae
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Fungal Proteins
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Nuclear Proteins
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Saccharomyces cerevisiae Proteins
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Transcription Factors
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Deoxyribonuclease EcoRI
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Adenosine Triphosphatases
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SNF2 protein, S cerevisiae