Botulinum toxin type A in the management of masseter muscle hypertrophy

J Oral Maxillofac Surg. 2005 Jan;63(1):20-4. doi: 10.1016/j.joms.2004.04.025.

Abstract

Purpose: We sought to evaluate the response of 6 patients with masseter muscle hypertrophy to botulinum toxin type A therapy.

Patients and methods: Six patients with unilateral or bilateral masseter muscle hypertrophy received intramuscular injection of the botulinum toxin type A. The functional and cosmetic results were evaluated as well as recurrence.

Results: In all patients, satisfactory regression of the masseter muscle hypertrophy occurred and mild muscular pain was relieved. Recurrence was observed in 2 cases.

Conclusions: The use of botulinum toxin type A in masseter muscle hypertrophy therapy was shown to be a successful and safe treatment method. This procedure to control parafunctional activities involving the masticatory muscles of patients appears to be useful.

MeSH terms

  • Adolescent
  • Adult
  • Botulinum Toxins, Type A / administration & dosage*
  • Female
  • Humans
  • Hypertrophy / drug therapy
  • Injections, Intramuscular
  • Male
  • Masseter Muscle*
  • Muscular Diseases / drug therapy*
  • Neuromuscular Agents / administration & dosage*
  • Recurrence
  • Treatment Outcome

Substances

  • Neuromuscular Agents
  • Botulinum Toxins, Type A