We used behavioral and emotional problem items to construct (a) nosologically based Diagnostic and Statistical Manual of Mental Disorders (DSM) oriented scales from experts' ratings of the items' consistency with DSM-IV (4th ed.; American Psychiatric Association, 1994) diagnostic categories, and (b) statistically based syndromes from factor analyses of adults' self-ratings and ratings of adults by people who knew them (N = 4,628). Quantified, operationally defined, and normed DSM-oriented scales and statistically based syndromes facilitate multitaxonomic approaches to the assessment of adult psychopathology. Psychometric properties and cross-informant correlations were similar for DSM-oriented scales and statistically derived syndromes. Statistical associations between phenotypically similar DSM-oriented scales and statistically based syndromes were moderate to strong. Multitaxonomic approaches can avoid reification of provisional taxa that may result from excessive reliance on a single taxonomic paradigm.