Irofulven: resurgence for alkylating therapy in cancer?

Cancer Biol Ther. 2004 Nov;3(11):1143-4. doi: 10.4161/cbt.3.11.1306. Epub 2004 Nov 12.
No abstract available

Publication types

  • Editorial

MeSH terms

  • Antineoplastic Agents, Alkylating / pharmacology*
  • Apoptosis / drug effects*
  • G1 Phase / drug effects*
  • Gene Expression Regulation / drug effects
  • Humans
  • Mitosis / drug effects*
  • Neoplasms / drug therapy*
  • Proto-Oncogene Proteins c-bcl-2 / genetics
  • Proto-Oncogene Proteins c-bcl-2 / metabolism
  • S Phase / drug effects*
  • Sesquiterpenes / pharmacology*

Substances

  • Antineoplastic Agents, Alkylating
  • Proto-Oncogene Proteins c-bcl-2
  • Sesquiterpenes
  • irofulven