T-cell mitogenic responses in fully xenogeneic chimeras (WF rat----B10 mouse) are restored by blocking the L-arginine-dependent nitric oxide pathway

Transplant Proc. 1992 Apr;24(2):499-500.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Arginine / analogs & derivatives*
  • Arginine / pharmacology
  • Cells, Cultured
  • Chimera / immunology*
  • Concanavalin A
  • Lymphocyte Activation* / drug effects
  • Mice
  • Mice, Inbred Strains
  • Nitric Oxide / metabolism*
  • Plant Lectins
  • Rats
  • Rats, Inbred Strains
  • T-Lymphocytes / drug effects
  • T-Lymphocytes / immunology*
  • Transplantation, Heterologous / immunology
  • omega-N-Methylarginine

Substances

  • Plant Lectins
  • Concanavalin A
  • omega-N-Methylarginine
  • Nitric Oxide
  • Arginine