Objective: Our objectives were to ascertain whether CO2 can be used as a contrast agent in venography during percutaneous vertebroplasty and to evaluate whether it might be capable of replacing nonionic iodinated contrast agents.
Conclusion: Intraosseous venography with CO2 contrast agent was slightly inferior to iodine venography in terms of its ability to visualize the vertebral bodies and perivertebral veins, but it remains a useful technique because no interference with optimal visualization of bone cement occurs during the cement injection when CO2 remains within the fracture cleft.