[Total hip arthroplasty for the treatment of septic hip arthritis in adults with sickle-cell disease]

Rev Chir Orthop Reparatrice Appar Mot. 2004 Oct;90(6):557-60. doi: 10.1016/s0035-1040(04)70430-4.
[Article in French]

Abstract

Purpose of the study: Septic hip arthritis is a recognized complication of sickle-cell disease. The incidence is difficult to assess but is significant since certain authors estimate that 11% of children with sickle-cell disease develop orthopedic complications. We report our experience with hip joint infection in adults with sickle-cell disease.

Material and methods: We diagnosed ten cases of hip joint infection in seven adults with sickle-cell disease. The characteristic feature of the septic arthritis was the development of a septic focus in a zone of osteonecrosis of the femoral head. Diagnosis was difficult due to the presence of prior hip disease and also the circumstances of development: other infectious foci, septicemia, distant osteomyelitis. The diagnosis was confirmed by joint puncture and isolation of the causal germ. Despite adapted antibiotics and immobilization with traction-suspension, hip joint destruction could not be prevented and all patients became bedridden. Surgery was therefore undertaken to remove the head and neck and institute local antibiotic treatment. A total hip prosthesis was implanted in all patients.

Results: At 2 to 12 years follow-up, all seven patients had nearly normal hip function (all 10 hips). Recurrent infection nevertheless developed in 2 hips, demonstrating the limitations of this technique.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Anemia, Sickle Cell / complications*
  • Arthritis, Infectious / complications*
  • Arthritis, Infectious / surgery*
  • Arthroplasty, Replacement, Hip*
  • Female
  • Hip Joint*
  • Humans
  • Male
  • Retrospective Studies