Dissemination of sulfonamide resistance genes (sul1, sul2, and sul3) in Portuguese Salmonella enterica strains and relation with integrons

Antimicrob Agents Chemother. 2005 Feb;49(2):836-9. doi: 10.1128/AAC.49.2.836-839.2005.

Abstract

In 200 sulfonamide-resistant Portuguese Salmonella isolates, 152 sul1, 74 sul2, and 14 sul3 genes were detected. Class 1 integrons were always associated with sul genes, including sul3 alone in some isolates. The sul3 gene has been identified in isolates from different sources and serotypes, which also carried a class 1 integron with aadA and dfrA gene cassettes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics*
  • Bacterial Proteins / metabolism
  • Conjugation, Genetic
  • Drug Resistance, Bacterial
  • Escherichia coli / genetics
  • Genes, Bacterial / genetics*
  • Humans
  • Integrons / genetics*
  • Portugal / epidemiology
  • Reverse Transcriptase Polymerase Chain Reaction
  • Salmonella Infections / epidemiology
  • Salmonella Infections / microbiology
  • Salmonella enterica / drug effects*
  • Salmonella enterica / genetics*
  • Sulfonamides / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Sul3 protein, Salmonella enterica
  • Sulfonamides