Cerebrovascular abnormalities in a population of children with neurofibromatosis type 1

Neurology. 2005 Feb 8;64(3):553-5. doi: 10.1212/01.WNL.0000150544.00016.69.

Abstract

Neurofibromatosis type 1 (NF1) is associated with vasculopathy, which may result in a variety of cerebrovascular complications. The purpose of this study was to evaluate the spectrum of cerebrovascular disease in a pediatric population with NF1. Of 316 patients with NF1 who underwent brain MRI, 8 (2.5%) children were reported to have an abnormality of the cerebrovascular system, including narrowed or ectatic vessels, vascular stenoses, aneurysm, and moyamoya.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Carotid Stenosis / etiology
  • Carotid Stenosis / pathology*
  • Child
  • Child, Preschool
  • Dilatation, Pathologic / etiology
  • Dilatation, Pathologic / pathology
  • Female
  • Follow-Up Studies
  • Humans
  • Imaging, Three-Dimensional
  • Infant
  • Infarction, Middle Cerebral Artery / etiology
  • Infarction, Middle Cerebral Artery / pathology*
  • Intracranial Aneurysm / etiology
  • Intracranial Aneurysm / pathology*
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Male
  • Moyamoya Disease / etiology
  • Moyamoya Disease / pathology*
  • Neurofibromatosis 1 / complications
  • Neurofibromatosis 1 / pathology*
  • Paresis / etiology
  • Retrospective Studies