[Neuropsychological evaluation of long-term therapy of Alzheimer's disease using different cerebrolysin dosages]

Zh Nevrol Psikhiatr Im S S Korsakova. 2005;105(1):52-5.
[Article in Russian]

Abstract

An open comparative randomized clinico-neuropsychological study of 4 cerebrolysin treatment courses was conducted during 19 months. The differences in long-term effects of different medication dosages (10 and 30 ml) were revealed. The higher cerebrolysin dose was more effictive for cognitive functioning of patients. In patients receiving a dosage of 10 ml, the disease progress was significantly more pronounced. The results obtained indicate that a course of cerebrolysin treatment in higher dosages significantly inhibited neurodegenerative process.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Alzheimer Disease / complications*
  • Alzheimer Disease / diagnosis
  • Alzheimer Disease / drug therapy*
  • Amino Acids / administration & dosage
  • Amino Acids / therapeutic use*
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / etiology*
  • Diagnostic and Statistical Manual of Mental Disorders
  • Drug Administration Schedule
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Nootropic Agents / administration & dosage
  • Nootropic Agents / therapeutic use*

Substances

  • Amino Acids
  • Nootropic Agents
  • cerebrolysin