The Stille reaction in the synthesis of carotenoid butenolides: synthesis of 6'-epi-peridinin

Belén Vaz; Rosana Alvarez; Reinhard Brückner; Angel R de Lera

doi:10.1021/ol0478281

The Stille reaction in the synthesis of carotenoid butenolides: synthesis of 6'-epi-peridinin

Org Lett. 2005 Feb 17;7(4):545-8. doi: 10.1021/ol0478281.

Authors

Belén Vaz¹, Rosana Alvarez, Reinhard Brückner, Angel R de Lera

Affiliation

¹ Departamento de Química Orgánica, Universidade de Vigo, 36200 Vigo, Spain.

PMID: 15704890
DOI: 10.1021/ol0478281

Abstract

A new strategy for carotenoid butenolides has been developed that is based in part in halogen-selective Stille cross-coupling of dihalogenated ylidenebutenolide segment 2 and highly functionalized alkenylstannanes. [reaction: see text]

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

4-Butyrolactone / analogs & derivatives*
4-Butyrolactone / chemical synthesis
Carotenoids / chemical synthesis*
Models, Molecular
Molecular Conformation
Palladium

Substances

peridinin
Carotenoids
Palladium
butenolide
4-Butyrolactone