Although information technology is utilized successfully in many industries, its use in health care-and home health care in particular--continues to lag. This column summarizes a recent article by Bakken and Hripcsak (2004) examining the potential for informatics to improve patient care quality in home health care by supporting evidence-based practices and patient safety. The authors provide definitions of the basic components of an informatics infrastructure e.g., data mining, digital sources of evidence, etc.--and recommend how to make an informatics infrastructure for the home health care industry a reality. Suggestions include: (1) integrating informatics into education and training; (2) creating public/private partnerships among government agencies, vendors, and industry associations; and (3) performing cost-effective analyses to determine the optimal uses of specific technologies.