Enantioselective synthesis of homoallylic alcohols via a chiral In(III)-PYBOX complex

Chem Commun (Camb). 2005 Feb 28:(8):1010-2. doi: 10.1039/b415550e. Epub 2005 Jan 5.

Abstract

In the presence of 20 mol% of a chiral catalytic complex prepared from In(OTf)(3) and chiral PYBOX, allyltributylstannane reacted with aldehydes to afford the corresponding homoallylic alcohols in moderate to high enantioselectivities (60-93% ee).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alcohols / chemical synthesis
  • Alcohols / chemistry*
  • Allyl Compounds / chemical synthesis
  • Allyl Compounds / chemistry*
  • Macromolecular Substances
  • Molecular Structure
  • Organometallic Compounds / chemistry*
  • Oxazoles / chemistry*
  • Pyridines / chemistry*
  • Stereoisomerism

Substances

  • Alcohols
  • Allyl Compounds
  • Macromolecular Substances
  • Organometallic Compounds
  • Oxazoles
  • Pyridines
  • indium(III)-PYBOX