Microtubule cytoskeleton: a new twist at the end

Torsten Wittmann; Arshad Desai

doi:10.1016/j.cub.2005.02.010

Microtubule cytoskeleton: a new twist at the end

Curr Biol. 2005 Feb 22;15(4):R126-9. doi: 10.1016/j.cub.2005.02.010.

Authors

Torsten Wittmann¹, Arshad Desai

Affiliation

¹ The Scripps Research Institute, Department of Cell Biology, 10550 North Torrey Pines Road, La Jolla, California 92037, USA. [email protected]

PMID: 15723782
DOI: 10.1016/j.cub.2005.02.010

Abstract

A diverse group of proteins known as +TIPs specifically recognize the growing plus ends of microtubules in cells. Two recent papers on one such protein, CLIP-170, provide new insights into the cellular functions of +TIPs as well as the mechanism by which they track microtubule ends.

Publication types

Review

MeSH terms

Cytoskeleton / metabolism*
Dyneins / metabolism
Microtubule-Associated Proteins / metabolism*
Microtubules / metabolism*
Models, Biological*
Neoplasm Proteins
Protein Binding
Yeasts

Substances

Microtubule-Associated Proteins
Neoplasm Proteins
cytoplasmic linker protein 170
Dyneins