Fluorometric sensing of the salt-induced B-Z DNA transition by combination of two pyrene-labeled nucleobases

Chem Commun (Camb). 2005 Mar 7:(9):1128-30. doi: 10.1039/b416965d. Epub 2005 Jan 17.

Abstract

We have developed a new fluorescent DNA sensor containing two pyrene-labeled nucleobases, (Pet)G and (Py)C, and the fluorescence color was altered by the salt-induced B-Z DNA transition.

Publication types

  • Evaluation Study

MeSH terms

  • Base Composition
  • DNA, Z-Form / chemistry*
  • Fluorescent Dyes / chemistry*
  • Fluorometry / methods*
  • Molecular Structure
  • Pyrenes / chemistry*
  • Sodium Chloride / chemistry*

Substances

  • DNA, Z-Form
  • Fluorescent Dyes
  • Pyrenes
  • Sodium Chloride
  • pyrene