Quetiapine-induced myoclonus

Int Clin Psychopharmacol. 2005 Mar;20(2):119-20. doi: 10.1097/00004850-200503000-00011.

Abstract

We report a case of myoclonus induced by quetiapine. A 64-year-old man with schizophrenia developed myoclonic jerks when given higher doses of quetiapine. These movements were dose-related and completely abated on reducing the dose. To our knowledge, these movements have not been reported previously as an adverse effect of quetiapine.

Publication types

  • Case Reports

MeSH terms

  • Antipsychotic Agents / administration & dosage
  • Antipsychotic Agents / adverse effects*
  • Antipsychotic Agents / therapeutic use
  • Dibenzothiazepines / administration & dosage
  • Dibenzothiazepines / adverse effects*
  • Dibenzothiazepines / therapeutic use
  • Dose-Response Relationship, Drug
  • Electrocardiography
  • Humans
  • Male
  • Middle Aged
  • Myoclonus / chemically induced*
  • Myoclonus / physiopathology
  • Quetiapine Fumarate
  • Schizophrenia, Paranoid / complications
  • Schizophrenia, Paranoid / drug therapy

Substances

  • Antipsychotic Agents
  • Dibenzothiazepines
  • Quetiapine Fumarate