Mycgranol, a new diterpene from the marine sponge Mycale aff. graveleyi

Amira Rudi; Yehuda Benayahu; Yoel Kashman

doi:10.1021/np0497550

Mycgranol, a new diterpene from the marine sponge Mycale aff. graveleyi

J Nat Prod. 2005 Feb;68(2):280-1. doi: 10.1021/np0497550.

Authors

Amira Rudi¹, Yehuda Benayahu, Yoel Kashman

Affiliation

¹ School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel-Aviv University, Ramat Aviv 69978, Israel.

PMID: 15730263
DOI: 10.1021/np0497550

Abstract

Mycgranol, a new isocopalane diterpene (methyl 1beta-hydroxy-2-oxoisocopalanoate) was isolated from the Kenyan sponge Mycale (Aegogropila) aff. graveleyi. The structure of the compound was elucidated by interpretation of MS, COSY, HMQC, HMBC, and ROESY data. The absolute configuration of mycgranol was determined to be the same as that of the nudibranch isocopalane diterpenes rather than that of the ent-compounds known from sponges of the genus Spongia.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Diterpenes* / chemistry
Diterpenes* / classification
Diterpenes* / isolation & purification*
Kenya
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Porifera / chemistry*

Substances

Diterpenes
mycgranol