Physaloside A, an acylated sucrose ester from Physalis viscosa

Simon P B Ovenden; Jin Yu; Jill Bernays; Soo San Wan; Larissa J Christophidis; Gian Sberna; R Murray Tait; Howard G Wildman; Dominique Lebeller; John Lowther; Neville G Walsh; Barbara M Meurer-Grimes

doi:10.1021/np049746r

Physaloside A, an acylated sucrose ester from Physalis viscosa

J Nat Prod. 2005 Feb;68(2):282-4. doi: 10.1021/np049746r.

Authors

Simon P B Ovenden¹, Jin Yu, Jill Bernays, Soo San Wan, Larissa J Christophidis, Gian Sberna, R Murray Tait, Howard G Wildman, Dominique Lebeller, John Lowther, Neville G Walsh, Barbara M Meurer-Grimes

Affiliation

¹ Cerylid Biosciences, 576 Swan Street, Richmond, Victoria 3121, Australia.

PMID: 15730264
DOI: 10.1021/np049746r

Abstract

Chemical investigations of the crude MeOH extract of Physalis viscosa led to the identification of the novel acylated sucrose ester physaloside A (1). The structure of 1 was determined by 2D NMR analysis, and the absolute configuration was determined by chemical degradation and comparison with authentic standards.

MeSH terms

Australia
Drug Screening Assays, Antitumor
Esters / chemistry
Esters / isolation & purification
Esters / pharmacology
Gram-Positive Bacteria / drug effects*
Microbial Sensitivity Tests
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Physalis / chemistry*
Plants, Medicinal / chemistry*
Sucrose* / analogs & derivatives*
Sucrose* / chemistry
Sucrose* / isolation & purification*
Sucrose* / pharmacology

Substances

Esters
physaloside A
Sucrose