Living-donor lobar lung transplantation for bronchiolitis obliterans after bone marrow transplantation

Yoshifumi Sano; Hiroshi Date; Itaru Nagahiro; Motoi Aoe; Nobuyoshi Shimizu

doi:10.1016/j.athoracsur.2003.09.111

Living-donor lobar lung transplantation for bronchiolitis obliterans after bone marrow transplantation

Ann Thorac Surg. 2005 Mar;79(3):1051-2. doi: 10.1016/j.athoracsur.2003.09.111.

Authors

Yoshifumi Sano¹, Hiroshi Date, Itaru Nagahiro, Motoi Aoe, Nobuyoshi Shimizu

Affiliation

¹ Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan. [email protected]

PMID: 15734441
DOI: 10.1016/j.athoracsur.2003.09.111

Abstract

We report a successful case of living-donor lobar lung transplantation (LDLLT) for severe bronchiolitis obliterans (BO) after bone marrow transplantation (BMT). The patient is a 29-year-old woman who underwent BMT because of aplastic anemia in 1995. In 1996, BO developed in the patient because of chronic graft-versus-host disease. In May 2000, a LDLLT was performed. Pulmonary function tests showed improvement of both vital capacity and forced expiratory volume in 1 second. At present, 91 months after BMT and 38 months after lung transplantation, the patient is in good health. LDLLT may offer a therapeutic option for the treatment of BO after BMT.

Publication types

Case Reports

MeSH terms

Adult
Bone Marrow Transplantation / adverse effects*
Bronchiolitis Obliterans / etiology*
Bronchiolitis Obliterans / surgery*
Female
Humans
Living Donors*
Lung Transplantation* / methods