Hand injuries in infants are an exciting challenge for those who treat pediatric trauma patients. We will review different hand injuries and provide basic rules for their treatment and followup. We will compare our experience with published results. When compared with adults, two main differences arise in treatment of pediatric hand injuries: children have an exceptional regenerative ability that allows procedures to be used that would not be useful in older patients (eg, replantation after avulsion injuries) and children have a high degree of cooperation with physicians. The main goal of treatment should be to have children return quickly to their daily leisure and academic activities.