Orbitofrontal cholesterol granuloma

J Clin Neurosci. 2005 Feb;12(2):206-9. doi: 10.1016/j.jocn.2003.09.006.

Abstract

Cholesterol granuloma of the orbital bones is a rare but readily recognisable condition. It is an osteolytic lesion with a granulomatous reaction surrounding cholesterol crystals, old haemorrhage and a fibrous capsule. There is a male preponderance and it usually occurs in young or middle-aged men. It is treatable with drainage and curettage via an orbitotomy, and craniotomy or wide bone removal is almost never required. Six cases of this condition were reviewed to highlight the typical clinical presentation, computed tomography and magnetic resonance results, and surgical management.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Cholesterol*
  • Frontal Lobe / pathology*
  • Frontal Lobe / surgery
  • Granuloma / diagnosis*
  • Granuloma / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Orbital Diseases / diagnosis*
  • Orbital Diseases / surgery
  • Tomography, X-Ray Computed

Substances

  • Cholesterol