Abstract
The association between a prothrombin mutation and the risk of thrombosis was analyzed in 214 patients with polycythemia vera or essential thrombocythemia. The rate for venous thrombotic events was 14.7/100 patient-years in patients with the prothrombin mutation compared to 0.8 in patients without the mutation (rate ratio 17.5).
MeSH terms
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Aged
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Cohort Studies
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Female
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Humans
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Male
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Middle Aged
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Mutation*
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Polycythemia Vera / complications
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Polycythemia Vera / epidemiology
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Polycythemia Vera / genetics
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Prothrombin / genetics*
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Thrombocythemia, Essential / complications
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Thrombocythemia, Essential / epidemiology
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Thrombocythemia, Essential / genetics
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Thrombosis / etiology
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Thrombosis / genetics*