Presence of DNA of human papillomavirus 16 but no other types in tumor-free tonsillar tissue

Renwei Chen; Peter Sehr; Tim Waterboer; Ilmo Leivo; Michael Pawlita; Antti Vaheri; Leena-Maija Aaltonen

doi:10.1128/JCM.43.3.1408-1410.2005

Presence of DNA of human papillomavirus 16 but no other types in tumor-free tonsillar tissue

J Clin Microbiol. 2005 Mar;43(3):1408-10. doi: 10.1128/JCM.43.3.1408-1410.2005.

Authors

Renwei Chen¹, Peter Sehr, Tim Waterboer, Ilmo Leivo, Michael Pawlita, Antti Vaheri, Leena-Maija Aaltonen

Affiliation

¹ Department of Virology, Haartman Institute, Haartmaninkatu 3, P.O. Box 21, 00014 University of Helsinki, Helsinki, Finland. [email protected]

Abstract

According to PCR, the prevalences of human papillomavirus (HPV) DNA were 6.3% (13 of 206) in tonsillitis or hypertrophic tonsillar tissues and 0.6% (1 of 174) in exfoliated cells from normal tonsils. HPV-16 was the only type detected in tonsillar tissues, but it did not appear to lead to L1 antibody production.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Antibodies, Viral / blood
Child
Child, Preschool
DNA, Viral / analysis*
Humans
Infant
Middle Aged
Palatine Tonsil / virology*
Papillomaviridae / classification*
Papillomaviridae / genetics
Polymerase Chain Reaction

Substances

Antibodies, Viral
DNA, Viral