Validating schizotaxia and its place in studies of preventing schizophrenia by psychopharmacological intervention

Essent Psychopharmacol. 2005;6(2):91-103.

Abstract

Schizotaxia is a stable syndrome of neuropsychological deficits and negative symptoms found in relatives of schizophrenic patients. These may represent special vulnerability to schizophrenia. Five areas of deficit are enumerated and suggestions as to the potential value of pre-illness interventions are discussed.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Antipsychotic Agents / therapeutic use*
  • Disease Susceptibility
  • Family
  • Humans
  • Psychiatric Status Rating Scales
  • Schizophrenia / classification
  • Schizophrenia / genetics
  • Schizophrenia / prevention & control*
  • Schizophrenic Psychology*
  • Schizotypal Personality Disorder / genetics
  • Schizotypal Personality Disorder / prevention & control

Substances

  • Antipsychotic Agents