Primary mediastinal large B-cell lymphoma in an HIV-infected patient

Am J Med Sci. 2005 Mar;329(3):136-8. doi: 10.1097/00000441-200503000-00004.

Abstract

HIV-related non-Hodgkin lymphoma is well documented in the literature. We report a case of an HIV-infected patient who presents with primary mediastinal large B-cell lymphoma. On review of the literature, this appears to be the first documented case of this subtype of large B-cell non-Hodgkin lymphoma seen in an HIV-infected patient. Our patient received CHOP (cyclophosphamide, hydroxydaunomycin, Oncovin, prednisone) chemotherapy with granulocyte colony-stimulating factor support but unfortunately died a few days later.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cyclophosphamide / therapeutic use
  • Doxorubicin / therapeutic use
  • Fatal Outcome
  • Female
  • Humans
  • Lymphoma, AIDS-Related / diagnosis*
  • Lymphoma, AIDS-Related / drug therapy
  • Lymphoma, Large B-Cell, Diffuse / diagnosis*
  • Lymphoma, Large B-Cell, Diffuse / drug therapy
  • Mediastinal Neoplasms / diagnosis*
  • Mediastinal Neoplasms / drug therapy
  • Prednisone / therapeutic use
  • Vincristine / therapeutic use

Substances

  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisone

Supplementary concepts

  • CHOP protocol