Re: Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer

J Natl Cancer Inst. 2005 Mar 16;97(6):461-2; author reply 462-3. doi: 10.1093/jnci/dji076.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Carcinoma, Non-Small-Cell Lung / drug therapy
  • Carcinoma, Non-Small-Cell Lung / metabolism*
  • Carcinoma, Non-Small-Cell Lung / pathology
  • ErbB Receptors / genetics*
  • ErbB Receptors / metabolism
  • Gefitinib
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / metabolism*
  • Lung Neoplasms / pathology
  • Lymph Nodes / metabolism
  • Lymphatic Metastasis
  • Mutation
  • Phosphorylation / drug effects
  • Protein Serine-Threonine Kinases / metabolism*
  • Proto-Oncogene Proteins / metabolism*
  • Proto-Oncogene Proteins c-akt
  • Quinazolines / therapeutic use*

Substances

  • Antineoplastic Agents
  • Proto-Oncogene Proteins
  • Quinazolines
  • ErbB Receptors
  • AKT1 protein, human
  • Protein Serine-Threonine Kinases
  • Proto-Oncogene Proteins c-akt
  • Gefitinib