Radiation injury to the liver after intensity-modulated radiation therapy in patients with mesothelioma: an unusual CT appearance

AJR Am J Roentgenol. 2005 Apr;184(4):1091-5. doi: 10.2214/ajr.184.4.01841091.

Abstract

Objective: We sought to report the unusual distribution of radiation-induced injury to the liver in patients with mesothelioma after extrapleural pneumonectomy and intensity-modulated radiation therapy (IMRT).

Conclusion: Abnormal hepatic enhancement after extrapleural pneumonectomy and IMRT is common in patients with mesothelioma. Knowledge of the early occurrence and typical location and appearance of IMRT-induced injury can be useful in preventing misinterpretation as metastatic disease or recurrent tumor.

MeSH terms

  • Aged
  • Contrast Media
  • Female
  • Humans
  • Iohexol
  • Liver / diagnostic imaging*
  • Liver / radiation effects*
  • Liver Function Tests
  • Male
  • Mesothelioma / radiotherapy*
  • Mesothelioma / surgery
  • Middle Aged
  • Pleural Neoplasms / radiotherapy*
  • Pleural Neoplasms / surgery
  • Pneumonectomy
  • Radiation Injuries / diagnostic imaging*
  • Radiotherapy Dosage
  • Retrospective Studies
  • Tomography, X-Ray Computed

Substances

  • Contrast Media
  • Iohexol