Thrombocytopenia and the risks of intraocular surgery

Ophthalmic Surg Lasers Imaging. 2005 Mar-Apr;36(2):103-7.

Abstract

Background and objective: In thrombocytopenia, a hemorrhagic diathesis is usually present due to a low platelet count and has been related to the development of cataracts and retinopathy. The concomitant administration of nonsteroidal anti-inflammatory drugs can increase the hemorrhagic diathesis. The purpose of this study was to investigate the impact of thrombocytopenia during and after intraocular surgery.

Patients and methods: A retrospective study of medical files of patients who had undergone cataract and glaucoma filtering surgery and were diagnosed as having thrombocytopenia between 1994--1995 and 1998--1999 was conducted. Eight patients with a total of 11 surgical procedures were included in this study.

Results: Hemorrhagic complications occurred in 2 of the 11 procedures, for an incidence of 18%. These 2 cases are described in detail.

Conclusions: The current study confirms that thrombocytopenia is a significant risk factor for perioperative bleeding in ocular surgery. A routine questionnaire should be completed before ocular surgery and a complete blood cell count obtained in suspect cases. Consultation with a hematologist is warranted in cases of thrombocytopenia.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Aged
  • Cataract / blood
  • Exfoliation Syndrome / blood
  • Exfoliation Syndrome / surgery*
  • Eye Hemorrhage / blood
  • Eye Hemorrhage / etiology*
  • Eye Hemorrhage / surgery
  • Female
  • Glaucoma, Open-Angle / blood
  • Glaucoma, Open-Angle / surgery*
  • Humans
  • Lens Implantation, Intraocular
  • Macular Degeneration / blood
  • Macular Degeneration / surgery
  • Middle Aged
  • Phacoemulsification*
  • Platelet Count
  • Postoperative Hemorrhage / blood
  • Postoperative Hemorrhage / etiology*
  • Postoperative Hemorrhage / surgery
  • Purpura, Thrombocytopenic, Idiopathic / blood
  • Purpura, Thrombocytopenic, Idiopathic / complications*
  • Purpura, Thrombocytopenic, Idiopathic / diagnosis
  • Retrospective Studies
  • Risk Factors
  • Trabeculectomy*
  • Vitrectomy