Life-threatening airway obstruction caused by mediastinal germinoma in a 9-year-old girl

J Pediatr Surg. 2005 Mar;40(3):588-90. doi: 10.1016/j.jpedsurg.2004.11.021.

Abstract

The authors report a case of a 9-year-old girl with a mediastinal germinoma that required emergent surgical extirpation because of tracheal compression and asphyxia. The tumor was successfully debulked under general anesthesia with the capability of extracorporeal circulation immediately available. Postoperatively, the tumor responded to adjuvant chemotherapy and irradiation and the patient survived without evidence of recurrence.

Publication types

  • Case Reports

MeSH terms

  • Airway Obstruction / etiology*
  • Anesthesia, General
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Asphyxia / etiology
  • Asthma / diagnosis
  • Bleomycin / administration & dosage
  • Carboplatin / administration & dosage
  • Chemotherapy, Adjuvant
  • Child
  • Combined Modality Therapy
  • Contraindications
  • Diagnostic Errors
  • Dyspnea / etiology
  • Emergencies
  • Epilepsy, Generalized / etiology
  • Etoposide / administration & dosage
  • Female
  • Germinoma / complications*
  • Germinoma / diagnosis
  • Germinoma / drug therapy
  • Germinoma / radiotherapy
  • Germinoma / surgery
  • Humans
  • Hypoxia / etiology
  • Mediastinal Neoplasms / complications*
  • Mediastinal Neoplasms / diagnosis
  • Mediastinal Neoplasms / drug therapy
  • Mediastinal Neoplasms / radiotherapy
  • Mediastinal Neoplasms / surgery
  • Radiotherapy, Adjuvant
  • Remission Induction
  • Tomography, X-Ray Computed
  • Tracheal Stenosis / etiology*

Substances

  • Bleomycin
  • Etoposide
  • Carboplatin

Supplementary concepts

  • JEB protocol