[Cogan's syndrome revealed by haemorrhagic glairous diarrhoea]

Presse Med. 2005 Feb 26;34(4):289-92. doi: 10.1016/s0755-4982(05)83908-9.
[Article in French]

Abstract

Introduction: Cogan's syndrome is defined by the combination of non syphilitic interstitial keratitis and inner ear dysfunction, similar to Meniere's disease.

Observation: Cogan's syndrome was revealed by haemorrhagic glaireous diarrhoea in a 21 year-old woman whose medical history included Hirschsprung's disease. Cerebral MRI revealed viral-like bilateral neuritis of the eighth cranial nerve, never described in the literature before. The auditory and visual disorders regressed after treatment with corticosteroids.

Conclusion: The early diagnosis of Cogan's syndrome permits the cure of the visual and auditory and notably inner ear symptoms with corticosteroid therapy.

Publication types

  • Case Reports
  • Comparative Study
  • English Abstract

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use
  • Audiometry
  • Cochlear Nerve*
  • Diagnosis, Differential
  • Diarrhea / etiology*
  • Female
  • Hearing Loss, Bilateral / complications*
  • Hearing Loss, Bilateral / drug therapy
  • Humans
  • Keratitis / complications*
  • Keratitis / diagnosis
  • Keratitis / drug therapy
  • Labyrinth Diseases / complications*
  • Labyrinth Diseases / diagnosis
  • Labyrinth Diseases / drug therapy
  • Magnetic Resonance Imaging
  • Meniere Disease / diagnosis
  • Prednisone / administration & dosage
  • Prednisone / therapeutic use
  • Prognosis
  • Syndrome
  • Time Factors
  • Treatment Outcome
  • Vestibulocochlear Nerve Diseases / complications
  • Vestibulocochlear Nerve Diseases / diagnosis*
  • Vestibulocochlear Nerve Diseases / drug therapy

Substances

  • Anti-Inflammatory Agents
  • Prednisone