Abstract
We prospectively studied the initial results of 6 months of generic efavirenz-based therapy on the plasma viral load in 40 patients at YRG Centre for AIDS Research and Education, a tertiary HIV referral centre in southern India. The median baseline plasma viral load was 259,000 copies/ml and at 6 months 95% of patients had plasma viral loads less than 400 copies/ml. The data support the use of generic non-nucleoside reverse transcriptase inhibitor-based regimens in resource-limited settings.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Adult
-
Alkynes
-
Anti-HIV Agents / administration & dosage*
-
Antiretroviral Therapy, Highly Active
-
Benzoxazines
-
Cyclopropanes
-
Drugs, Generic
-
Female
-
HIV Infections / drug therapy*
-
HIV-1*
-
Humans
-
India
-
Lamivudine / administration & dosage*
-
Male
-
Middle Aged
-
Oxazines / administration & dosage*
-
Prospective Studies
-
Tablets
-
Treatment Outcome
-
Viral Load
-
Zidovudine / administration & dosage*
Substances
-
Alkynes
-
Anti-HIV Agents
-
Benzoxazines
-
Cyclopropanes
-
Drugs, Generic
-
Oxazines
-
Tablets
-
Lamivudine
-
Zidovudine
-
efavirenz