pFind: a novel database-searching software system for automated peptide and protein identification via tandem mass spectrometry

Bioinformatics. 2005 Jul 1;21(13):3049-50. doi: 10.1093/bioinformatics/bti439. Epub 2005 Apr 7.

Abstract

Research in proteomics requires powerful database-searching software to automatically identify protein sequences in a complex protein mixture via tandem mass spectrometry. In this paper, we describe a novel database-searching software system called pFind (peptide/protein Finder), which employs an effective peptide-scoring algorithm that we reported earlier. The pFind server is implemented with the C++ STL, .Net and XML technologies. As a result, high speed and good usability of the software are achieved.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Artificial Intelligence
  • Database Management Systems*
  • Databases, Protein*
  • Gene Expression Profiling / methods
  • Mass Spectrometry / methods*
  • Proteins / analysis
  • Proteins / chemistry*
  • Proteins / classification
  • Sequence Alignment / methods*
  • Sequence Analysis, Protein / methods*
  • Software*
  • User-Computer Interface

Substances

  • Proteins