Comparison of the unsaturated iron-binding capacity with transferrin saturation as a screening test to detect C282Y homozygotes for hemochromatosis in 101,168 participants in the hemochromatosis and iron overload screening (HEIRS) study

MeSH terms

• Adult
• Aged
• Aged, 80 and over
• Female
• Hemochromatosis / blood
• Hemochromatosis / diagnosis*
• Hemochromatosis / genetics
• Hemochromatosis Protein
• Histocompatibility Antigens Class I / genetics*
• Homozygote
• Humans
• Iron / blood*
• Iron Overload / diagnosis*
• Male
• Membrane Proteins / genetics*
• Middle Aged
• Mutation
• Protein Binding
• ROC Curve
• Sensitivity and Specificity
• Transferrin / metabolism*