Abstract
Genome-wide analysis of temporal gene expression profiles in Escherichia coli following exposure to cadmium revealed a shift to anaerobic metabolism and induction of several stress response systems. Disruption in the transcription of genes encoding ribosomal proteins and zinc-binding proteins may partially explain the molecular mechanisms of cadmium toxicity.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adaptation, Physiological
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Biological Transport
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Cadmium / pharmacology*
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Carrier Proteins / genetics
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Coliphages
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DNA Transposable Elements
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Escherichia coli / drug effects*
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Escherichia coli / genetics
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Escherichia coli Proteins / genetics
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Gene Expression Regulation, Bacterial*
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Oligonucleotide Array Sequence Analysis
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Plasmids
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Protein Processing, Post-Translational
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Ribosomal Proteins / genetics
Substances
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Carrier Proteins
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DNA Transposable Elements
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Escherichia coli Proteins
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Ribosomal Proteins
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zinc-binding protein
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Cadmium