Delayed contrast-enhanced MRI of the aortic wall in Takayasu's arteritis: initial experience

AJR Am J Roentgenol. 2005 May;184(5):1427-31. doi: 10.2214/ajr.184.5.01841427.

Abstract

Objective: Delayed contrast-enhanced MRI is increasingly being used for cardiac viability imaging. Takayasu's arteritis is a rare inflammatory disorder of unknown cause that affects the aorta, its major branches, and the pulmonary artery; it is characterized by inflammation and fibrosis in the arterial wall. We report our initial experience with seven patients (six women, one man; age range, 25-62 years) with delayed (20 min) gadolinium-enhanced MRI (inversion recovery prepared gated fast gradient-echo pulse sequence) in patients with known Takayasu's arteritis.

Conclusion: Patients with Takayasu's arteritis (particularly those with abnormal laboratory values) have evidence of delayed hyper-enhancement on delayed contrast-enhanced MRI. Thus, delayed contrast-enhanced MRI might be a useful technique to identify inflammation in arterial wall.

MeSH terms

  • Adult
  • Aortic Diseases / pathology*
  • Contrast Media
  • Disease Progression
  • Female
  • Gadolinium DTPA
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Takayasu Arteritis / pathology*

Substances

  • Contrast Media
  • Gadolinium DTPA