Primary breast lymphoma cytologic diagnosis

Arch Pathol Lab Med. 2005 May;129(5):694-6. doi: 10.5858/2005-129-0694-PBLCD.

Abstract

Primary non-Hodgkin lymphoma of the breast is a rare pathology, and bilateral involvement is exceptional. We report a case of bilateral primary non-Hodgkin lymphoma of the breast in a 40-year-old woman. Predominantly atypical lymphocytes and rare plasma cells were found in the microscopic evaluation of the fine-needle aspiration biopsy of the right and left breasts. Microscopic findings of the incisional biopsy of the left breast were in accordance with non-Hodgkin diffuse large B-cell lymphoma. The patient received systemic chemotherapy and is alive with no evidence of recurrence for 2 years.

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biomarkers, Tumor / analysis
  • Biopsy, Fine-Needle*
  • Breast Neoplasms / chemistry
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / pathology*
  • Cyclophosphamide / administration & dosage
  • Doxorubicin / administration & dosage
  • Female
  • Humans
  • Immunohistochemistry
  • Lymphoma, Non-Hodgkin / chemistry
  • Lymphoma, Non-Hodgkin / diagnostic imaging
  • Lymphoma, Non-Hodgkin / pathology*
  • Mammography
  • Prednisone / administration & dosage
  • Treatment Outcome
  • Vincristine / administration & dosage

Substances

  • Biomarkers, Tumor
  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisone

Supplementary concepts

  • CHOP protocol