Abstract
Pregnant sows were immunized by oral application of live E. coli. The effect of immunization was demonstrated by measuring the titers of anti-K88 antibodies in sow serum, colostrum and milk as well as in piglet sera using enzyme-linked immunosorbent assays. The isotype involved in anti-K88 reactivity was found to be IgA. By comparing IgA-titers in colostrum and milk, the local production of this Ig-class in the mammary gland is suggested.
MeSH terms
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Administration, Oral
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Animals
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Animals, Newborn
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Antibodies, Bacterial / biosynthesis*
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Antibodies, Bacterial / blood
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Antigens, Bacterial / immunology*
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Colostrum / immunology
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Enzyme-Linked Immunosorbent Assay / veterinary
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Escherichia coli / immunology*
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Escherichia coli Infections / prevention & control
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Escherichia coli Infections / veterinary
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Escherichia coli Proteins / immunology*
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Female
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Fimbriae Proteins / immunology*
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Immunoglobulin A / biosynthesis*
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Immunoglobulin A / blood
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Milk / immunology
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Pregnancy
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Swine / blood
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Swine / immunology*
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Swine Diseases / prevention & control
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Vaccination / veterinary*
Substances
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Antibodies, Bacterial
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Antigens, Bacterial
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Escherichia coli Proteins
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Immunoglobulin A
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K88 antigen, E coli
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Fimbriae Proteins