Abstract
We describe 2 children with prolonged fever of unknown origin and prominent skeletal pain who had multifocal bone disease caused by Bartonella infection. Initial radiologic studies, including plain films, radionuclide scintigraphy and computed tomography, yielded negative results. In both cases, magnetic resonance imaging revealed multiple enhancing bone marrow lesions consistent with clinical symptoms. Microbiologic diagnoses were established serologically.
MeSH terms
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Animals
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Anti-Bacterial Agents / therapeutic use
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Bartonella henselae / isolation & purification*
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Bone Marrow / microbiology
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Bone Marrow / pathology*
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Cat-Scratch Disease / complications
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Cat-Scratch Disease / diagnosis*
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Child
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Child, Preschool
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Female
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Follow-Up Studies
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Humans
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Magnetic Resonance Imaging / methods
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Male
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Osteomyelitis / diagnosis*
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Osteomyelitis / drug therapy
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Osteomyelitis / microbiology*
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Risk Assessment
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Severity of Illness Index
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Tomography, X-Ray Computed / methods
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Treatment Outcome